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Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia

Alan S. Wayne, Nirali N. Shah, Deepa Bhojwani, Lewis B. Silverman, James A. Whitlock, Maryalice Stetler-Stevenson, Weili Sun, Meina Liang, Jie Yang, Robert J. Kreitman, Mark C. Lanasa and Ira Pastan

Article Information

Citation 
vol. 130 no. 14 1620-1627
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted February 21, 2017
  • Accepted July 27, 2017
  • Published online October 5, 2017.

Article Versions


Contributors 
  • Alan S. Wayne, 1Children’s Center for Cancer and Blood Diseases, Division of Hematology, Oncology, and Blood and Marrow Transplantation, Children’s Hospital Los Angeles, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; 2Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD; 3Laboratory of Molecular Biology, CCR, NCI, NIH, Bethesda, MD;
  • Nirali N. Shah, 2Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD;
  • Deepa Bhojwani, 1Children’s Center for Cancer and Blood Diseases, Division of Hematology, Oncology, and Blood and Marrow Transplantation, Children’s Hospital Los Angeles, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; 4St Jude Children’s Research Hospital, Memphis, TN;
  • Lewis B. Silverman, 5Pediatric Hematologic Malignancies Center, Dana-Farber Cancer Institute/Boston Children’s Hospital, Boston, MA;
  • James A. Whitlock, 6Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada;
  • Maryalice Stetler-Stevenson, 7Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD; and
  • Weili Sun, 1Children’s Center for Cancer and Blood Diseases, Division of Hematology, Oncology, and Blood and Marrow Transplantation, Children’s Hospital Los Angeles, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA;
  • Meina Liang, 8MedImmune, Gaithersburg, MD
  • Jie Yang, 8MedImmune, Gaithersburg, MD
  • Robert J. Kreitman, 3Laboratory of Molecular Biology, CCR, NCI, NIH, Bethesda, MD;
  • Mark C. Lanasa, 8MedImmune, Gaithersburg, MD
  • Ira Pastan, 3Laboratory of Molecular Biology, CCR, NCI, NIH, Bethesda, MD;

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