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Table of Contents

May 04, 2017; 129 (18)

INSIDE BLOOD COMMENTARIES

BLOOD SPOTLIGHT

CLINICAL TRIALS AND OBSERVATIONS

  • Efficacy and tolerability of nivolumab after allogeneic transplantation for relapsed Hodgkin lymphoma
    Charles Herbaux, Jordan Gauthier, Pauline Brice, Elodie Drumez, Loic Ysebaert, Hélène Doyen, Luc Fornecker, Krimo Bouabdallah, Guillaume Manson, Hervé Ghesquières, Reza Tabrizi, Eric Hermet, Julien Lazarovici, Anne Thiebaut-Bertrand, Adrien Chauchet, Hélène Demarquette, Eileen Boyle, Roch Houot, Ibrahim Yakoub-Agha and Franck Morschhauser

HEMATOPOIESIS AND STEM CELLS

  • Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress
    Wei Shi, Therese Vu, Didier Boucher, Anna Biernacka, Jules Nde, Raj K. Pandita, Jasmin Straube, Glen M. Boyle, Fares Al-Ejeh, Purba Nag, Jessie Jeffery, Janelle L. Harris, Amanda L. Bain, Marta Grzelak, Magdalena Skrzypczak, Abhishek Mitra, Norbert Dojer, Nicola Crosetto, Nicole Cloonan, Olivier J. Becherel, John Finnie, Jeffrey R. Skaar, Carl R. Walkley, Tej K. Pandita, Maga Rowicka, Krzysztof Ginalski, Steven W. Lane and Kum Kum Khanna
  • PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells
    Cécile Naudin, Aurore Hattabi, Fabio Michelet, Ayda Miri-Nezhad, Aissa Benyoucef, Françoise Pflumio, François Guillonneau, Serge Fichelson, Isabelle Vigon, Isabelle Dusanter-Fourt and Evelyne Lauret

LYMPHOID NEOPLASIA

  • IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
    Shubham Pandey, Frédéric Mourcin, Tony Marchand, Saba Nayar, Marion Guirriec, Céline Pangault, Céline Monvoisin, Patricia Amé-Thomas, Fabien Guilloton, Joelle Dulong, Mark Coles, Thierry Fest, Anja Mottok, Francesca Barone and Karin Tarte
  • Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia
    Lian Xu, Nicholas Tsakmaklis, Guang Yang, Jiaji G. Chen, Xia Liu, Maria Demos, Amanda Kofides, Christopher J. Patterson, Kirsten Meid, Joshua Gustine, Toni Dubeau, M. Lia Palomba, Ranjana Advani, Jorge J. Castillo, Richard R. Furman, Zachary R. Hunter and Steven P. Treon

MYELOID NEOPLASIA

PLATELETS AND THROMBOPOIESIS

  • Elevated hematocrit enhances platelet accumulation following vascular injury
    Bethany L. Walton, Marcus Lehmann, Tyler Skorczewski, Lori A. Holle, Joan D. Beckman, Jeremy A. Cribb, Micah J. Mooberry, Adam R. Wufsus, Brian C. Cooley, Jonathan W. Homeister, Rafal Pawlinski, Michael R. Falvo, Nigel S. Key, Aaron L. Fogelson, Keith B. Neeves and Alisa S. Wolberg

THROMBOSIS AND HEMOSTASIS

TRANSFUSION MEDICINE

  • T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10
    Rick Kapur, Michael Kim, Rukhsana Aslam, Mark J. McVey, Arata Tabuchi, Alice Luo, Jonathan Liu, Yuan Li, Shanjeevan Shanmugabhavananthan, Edwin R. Speck, Anne Zufferey, George Yousef, Haibo Zhang, Matthew T. Rondina, Andrew S. Weyrich, Leendert Porcelijn, Wolfgang M. Kuebler, Arthur S. Slutsky and John W. Semple

TRANSPLANTATION

  • Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production
    Jing Du, Katelyn Paz, Ryan Flynn, Ante Vulic, Tara M. Robinson, Katie E. Lineburg, Kylie A. Alexander, Jingjing Meng, Sabita Roy, Angela Panoskaltsis-Mortari, Michael Loschi, Geoffrey R. Hill, Jonathan S. Serody, Ivan Maillard, David Miklos, John Koreth, Corey S. Cutler, Joseph H. Antin, Jerome Ritz, Kelli P. MacDonald, Timothy W. Schacker, Leo Luznik and Bruce R. Blazar

LETTERS TO BLOOD

  • Ventricular arrhythmias and sudden death in patients taking ibrutinib
    Benjamin L. Lampson, Lijian Yu, Robert J. Glynn, Jacqueline C. Barrientos, Eric D. Jacobsen, Versha Banerji, Jeffrey A. Jones, Renata Walewska, Kerry J. Savage, Gregory F. Michaud, Javid J. Moslehi and Jennifer R. Brown
  • More than 1 TP53 abnormality is a dominant characteristic of pure erythroid leukemia
    Guillermo Montalban-Bravo, Christopher B. Benton, Sa A. Wang, Farhad Ravandi, Tapan Kadia, Jorge Cortes, Naval Daver, Koichi Takahashi, Courtney DiNardo, Elias Jabbour, Gautam Borthakur, Marina Konopleva, Sherry Pierce, Carlos Bueso-Ramos, Keyur Patel, Steven Kornblau, Hagop Kantarjian, Ken H. Young, Guillermo Garcia-Manero and Michael Andreeff
  • Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia
    Ridhima Lal, Karin Lind, Ellen Heitzer, Peter Ulz, Kristina Aubell, Karl Kashofer, Jan M. Middeke, Christian Thiede, Eduard Schulz, Angelika Rosenberger, Sybille Hofer, Birgit Feilhauer, Beate Rinner, Vendula Svendova, Michael G. Schimek, Frank G. Rücker, Gerald Hoefler, Konstanze Döhner, Armin Zebisch, Albert Wölfler and Heinz Sill

BLOOD WORK