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H3B-8800, an Orally Bioavailable Modulator of the SF3b Complex, Shows Efficacy in Spliceosome-Mutant Myeloid Malignancies

Silvia Buonamici, Akihide Yoshimi, Michael Thomas, Michael Seiler, Betty Chan, Benjamin Caleb, Rachel Darman, Peter Fekkes, Craig Karr, Gregg F. Keaney, Virginia M. Klimek, Kaiko Kunii, Linda Lee, Stanley Chun-Wei Lee, Xiang Liu, Carol Meeske, Yoshiharu Mizui, Eric Padron, Eunice Park, Ermira Pazolli, Sudeep Prajapati, Justin Taylor, John Wang, Markus Warmuth, Lihua Yu, Ping Zhu, Omar Abdel-Wahab and Peter G Smith

Article Information

Citation 
vol. 128 no. 22 966

Print ISSN 
Online ISSN 
History 
  • Published online December 1, 2016.


Contributors 
  • Silvia Buonamici [PhD], 1H3 Biomedicine, Cambridge, MA
  • Akihide Yoshimi [MD PhD], 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
  • Michael Thomas, 1H3 Biomedicine, Cambridge, MA
  • Michael Seiler [PhD], 1H3 Biomedicine, Cambridge, MA
  • Betty Chan [PhD], 1H3 Biomedicine, Cambridge, MA
  • Benjamin Caleb, 1H3 Biomedicine, Cambridge, MA
  • Rachel Darman [PhD], 1H3 Biomedicine, Cambridge, MA
  • Peter Fekkes [PhD], 1H3 Biomedicine, Cambridge, MA
  • Craig Karr [PhD], 1H3 Biomedicine, Cambridge, MA
  • Gregg F. Keaney [PhD], 1H3 Biomedicine, Cambridge, MA
  • Virginia M. Klimek [MD], 3Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
  • Kaiko Kunii, 1H3 Biomedicine, Cambridge, MA
  • Linda Lee, 1H3 Biomedicine, Cambridge, MA
  • Stanley Chun-Wei Lee [PhD], 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
  • Xiang Liu [PhD], 1H3 Biomedicine, Cambridge, MA
  • Carol Meeske, 1H3 Biomedicine, Cambridge, MA
  • Yoshiharu Mizui [PhD], 1H3 Biomedicine, Cambridge, MA
  • Eric Padron [MD], 4Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 5H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
  • Eunice Park [PhD], 1H3 Biomedicine, Cambridge, MA
  • Ermira Pazolli [PhD], 1H3 Biomedicine, Cambridge, MA
  • Sudeep Prajapati [PhD], 1H3 Biomedicine, Cambridge, MA
  • Justin Taylor [MD], 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
  • John Wang [PhD], 1H3 Biomedicine, Cambridge, MA
  • Markus Warmuth [MD], 1H3 Biomedicine, Cambridge, MA
  • Lihua Yu [PhD], 1H3 Biomedicine, Cambridge, MA
  • Ping Zhu [MD], 1H3 Biomedicine, Cambridge, MA
  • Omar Abdel-Wahab [MD], 6Memorial Sloan Kettering Cancer Center, New York, NY
  • Peter G Smith [PhD], 1H3 Biomedicine, Cambridge, MA

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