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Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies

Thomas McKerrell, Thaidy Moreno, Hannes Ponstingl, Niccolo Bolli, João M. L. Dias, German Tischler, Vincenza Colonna, Bridget Manasse, Anthony Bench, David Bloxham, Bram Herman, Danielle Fletcher, Naomi Park, Michael A. Quail, Nicla Manes, Clare Hodkinson, Joanna Baxter, Jorge Sierra, Theodora Foukaneli, Alan J. Warren, Jianxiang Chi, Paul Costeas, Roland Rad, Brian Huntly, Carolyn Grove, Zemin Ning, Chris Tyler-Smith, Ignacio Varela, Mike Scott, Josep Nomdedeu, Ville Mustonen and George S. Vassiliou

Article Information

Citation 
vol. 128 no. 1 e1-e9
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted November 22, 2015
  • Accepted April 21, 2016
  • Published online July 7, 2016.

Article Versions


Contributors 
  • Thomas McKerrell, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
  • Thaidy Moreno, 4Instituto de Biomedicina y Biotecnología de Cantabria, Cantabria, Spain;
  • Hannes Ponstingl, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Niccolo Bolli, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; 5Division of Haematology, Fondazione IRCCS Istituto Nazionale dei Tumori, University of Milan, Milan, Italy;
  • João M. L. Dias, 6Cancer Molecular Diagnosis Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, United Kingdom;
  • German Tischler, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Vincenza Colonna, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; 7National Research Council, Institute of Genetics and Biophysics, Naples, Italy;
  • Bridget Manasse, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom;
  • Anthony Bench, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom;
  • David Bloxham, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom;
  • Bram Herman, 8Agilent Technologies, Cheadle, United Kingdom;
  • Danielle Fletcher, 8Agilent Technologies, Cheadle, United Kingdom;
  • Naomi Park, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Michael A. Quail, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Nicla Manes, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
  • Clare Hodkinson, 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
  • Joanna Baxter, 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
  • Jorge Sierra, 9Department of Haematology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain;
  • Theodora Foukaneli, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom;
  • Alan J. Warren, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom; 10Cambridge Institute for Medical Research, Cambridge, United Kingdom; 11Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom;
  • Jianxiang Chi, 12The Center for the Study of Haematological Malignancies, Nicosia, Cyprus; 13The Karaiskakio Foundation, Nicosia, Cyprus;
  • Paul Costeas, 12The Center for the Study of Haematological Malignancies, Nicosia, Cyprus; 13The Karaiskakio Foundation, Nicosia, Cyprus;
  • Roland Rad, 14Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; 15German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany;
  • Brian Huntly, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom; 10Cambridge Institute for Medical Research, Cambridge, United Kingdom; 11Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom;
  • Carolyn Grove, 16Department of Haematology, PathWest/Sir Charles Gairdner Hospital, Perth, Australia; and 17Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia
  • Zemin Ning, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Chris Tyler-Smith, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • Ignacio Varela, 4Instituto de Biomedicina y Biotecnología de Cantabria, Cantabria, Spain;
  • Mike Scott, 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
  • Josep Nomdedeu, 9Department of Haematology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain;
  • Ville Mustonen, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom;
  • George S. Vassiliou, 1Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; 2Department of Haematology, Haemato-oncology Diagnostic Service, Cambridge University Hospitals National Health Service Trust, Cambridge, United Kingdom; 3Department of Haematology, University of Cambridge, Cambridge, United Kingdom;

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