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Table of Contents

January 22, 2015; 125 (4)

INSIDE BLOOD COMMENTARIES

PLENARY PAPER

  • Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations
    Joshua D. Milner, Tiphanie P. Vogel, Lisa Forbes, Chi A. Ma, Asbjørg Stray-Pedersen, Julie E. Niemela, Jonathan J. Lyons, Karin R. Engelhardt, Yu Zhang, Nermina Topcagic, Elisha D. O. Roberson, Helen Matthews, James W. Verbsky, Trivikram Dasu, Alexander Vargas-Hernandez, Nidhy Varghese, Kenneth L. McClain, Lina B. Karam, Karen Nahmod, George Makedonas, Emily M. Mace, Hanne S. Sorte, Gøri Perminow, V. Koneti Rao, Michael P. O’Connell, Susan Price, Helen C. Su, Morgan Butrick, Joshua McElwee, Jason D. Hughes, Joseph Willet, David Swan, Yaobo Xu, Mauro Santibanez-Koref, Voytek Slowik, Darrell L. Dinwiddie, Christina E. Ciaccio, Carol J. Saunders, Seth Septer, Stephen F. Kingsmore, Andrew J. White, Andrew J. Cant, Sophie Hambleton and Megan A. Cooper

PERSPECTIVES

  • The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations
    Margherita Bodini, Chiara Ronchini, Luciano Giacò, Anna Russo, Giorgio E. M. Melloni, Lucilla Luzi, Domenico Sardella, Sara Volorio, Syed K. Hasan, Tiziana Ottone, Serena Lavorgna, Francesco Lo-Coco, Anna Candoni, Renato Fanin, Eleonora Toffoletti, Ilaria Iacobucci, Giovanni Martinelli, Alessandro Cignetti, Corrado Tarella, Loris Bernard, Pier Giuseppe Pelicci and Laura Riva

HOW I TREAT

CLINICAL TRIALS AND OBSERVATIONS

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY

  • Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3
    Emma M. Haapaniemi, Meri Kaustio, Hanna L. M. Rajala, Arjan J. van Adrichem, Leena Kainulainen, Virpi Glumoff, Rainer Doffinger, Heikki Kuusanmäki, Tarja Heiskanen-Kosma, Luca Trotta, Samuel Chiang, Petri Kulmala, Samuli Eldfors, Riku Katainen, Sanna Siitonen, Marja-Liisa Karjalainen-Lindsberg, Panu E. Kovanen, Timo Otonkoski, Kimmo Porkka, Kaarina Heiskanen, Arno Hänninen, Yenan T. Bryceson, Raija Uusitalo-Seppälä, Janna Saarela, Mikko Seppänen, Satu Mustjoki and Juha Kere
  • HGAL localization to cell membrane regulates B-cell receptor signaling
    Xiaoqing Lu, Renaud Sicard, Xiaoyu Jiang, Jessica N. Stockus, George McNamara, Midhat Abdulreda, Vincent T. Moy, Ralf Landgraf and Izidore S. Lossos

LYMPHOID NEOPLASIA

  • BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma
    Cristina Correia, Paula A. Schneider, Haiming Dai, Ahmet Dogan, Matthew J. Maurer, Amy K. Church, Anne J. Novak, Andrew L. Feldman, Xiaosheng Wu, Husheng Ding, X. Wei Meng, James R. Cerhan, Susan L. Slager, William R. Macon, Thomas M. Habermann, Judith E. Karp, Steven D. Gore, Neil E. Kay, Diane F. Jelinek, Thomas E. Witzig, Grzegorz S. Nowakowski and Scott H. Kaufmann
  • Activating STAT6 mutations in follicular lymphoma
    Mehmet Yildiz, Hongxiu Li, Denzil Bernard, Nisar A. Amin, Peter Ouillette, Siân Jones, Kamlai Saiya-Cork, Brian Parkin, Kathryn Jacobi, Kerby Shedden, Shaomeng Wang, Alfred E. Chang, Mark S. Kaminski and Sami N. Malek
  • A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults
    Virginia Perez-Andreu, Kathryn G. Roberts, Heng Xu, Colton Smith, Hui Zhang, Wenjian Yang, Richard C. Harvey, Debbie Payne-Turner, Meenakshi Devidas, I-Ming Cheng, William L. Carroll, Nyla A. Heerema, Andrew J. Carroll, Elizabeth A. Raetz, Julie M. Gastier-Foster, Guido Marcucci, Clara D. Bloomfield, Krzysztof Mrózek, Jessica Kohlschmidt, Wendy Stock, Steven M. Kornblau, Marina Konopleva, Elisabeth Paietta, Jacob M. Rowe, Selina M. Luger, Martin S. Tallman, Michael Dean, Esteban G. Burchard, Dara G. Torgerson, Feng Yue, Yanli Wang, Ching-Hon Pui, Sima Jeha, Mary V. Relling, William E. Evans, Daniela S. Gerhard, Mignon L. Loh, Cheryl L. Willman, Stephen P. Hunger, Charles G. Mullighan and Jun J. Yang

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION