Blood Journal
Leading the way in experimental and clinical research in hematology

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

  1. May S. Kung Sutherland1,
  2. Roland B. Walter2,3,
  3. Scott C. Jeffrey1,
  4. Patrick J. Burke1,
  5. Changpu Yu1,
  6. Heather Kostner1,
  7. Ivan Stone1,
  8. Maureen C. Ryan1,
  9. Django Sussman1,
  10. Robert P. Lyon1,
  11. Weiping Zeng1,
  12. Kimberly H. Harrington2,
  13. Kerry Klussman1,
  14. Lori Westendorf1,
  15. David Meyer1,
  16. Irwin D. Bernstein2,4,
  17. Peter D. Senter1,
  18. Dennis R. Benjamin1,
  19. Jonathan G. Drachman1, and
  20. Julie A. McEarchern1
  1. 1Department of Research & Translational Medicine, Seattle Genetics, Inc., Bothell, WA;
  2. 2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and
  3. 3Division of Hematology/Department of Medicine, and
  4. 4Department of Pediatrics, University of Washington, Seattle, WA
  1. Partially presented as a poster at the 54th annual meeting of the American Society of Hematology, Atlanta, GA, December 10, 2012.

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