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Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels

Mohammad Al-Tamimi, Chee Wee Tan, Jianlin Qiao, Gabrielle J. Pennings, Ashkan Javadzadegan, Andy S. C. Yong, Jane F. Arthur, Amanda K. Davis, Jing Jing, Fi-Tjen Mu, Justin R. Hamilton, Shaun P. Jackson, Andreas Ludwig, Michael C. Berndt, Christopher M. Ward, Leonard Kritharides, Robert K. Andrews and Elizabeth E. Gardiner

Article Information

Citation 
vol. 119 no. 18 4311-4320
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted October 18, 2011
  • Accepted March 8, 2012
  • Published online May 3, 2012.

Article Versions


Contributors 
  • Mohammad Al-Tamimi, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Chee Wee Tan, 2Northern Blood Research Centre, University of Sydney, Sydney, Australia;
  • Jianlin Qiao, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Gabrielle J. Pennings, 3ANZAC Research Institute and Department of Cardiology, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia;
  • Ashkan Javadzadegan, 4Department of Mechanical Engineering, University of Sydney, Sydney, Australia;
  • Andy S. C. Yong, 3ANZAC Research Institute and Department of Cardiology, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia;
  • Jane F. Arthur, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Amanda K. Davis, 5Department of Haematology, Alfred Hospital, Melbourne, Australia;
  • Jing Jing, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Fi-Tjen Mu, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Justin R. Hamilton, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Shaun P. Jackson, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Andreas Ludwig, 6Institute for Pharmacology and Toxicology and Interdisciplinary Center for Clinical Research, RWTH Aachen University, Aachen, Germany; and
  • Michael C. Berndt, 7Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland
  • Christopher M. Ward, 2Northern Blood Research Centre, University of Sydney, Sydney, Australia;
  • Leonard Kritharides, 3ANZAC Research Institute and Department of Cardiology, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia;
  • Robert K. Andrews, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;
  • Elizabeth E. Gardiner, 1Monash University, Australian Centre for Blood Diseases, Alfred Medical Research & Education Precinct, Melbourne, Australia;

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