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FNAIT: the fetus pleads guilty!

Cécile Kaplan

Article Figures & Data

Figures

  • FcRn a key factor in FNIT. (A) Fetal FcRn is required for FNIT. Low platelet counts are observed only in pups expressing fetal FcRn delivered from immunized β3−/−FcRn−/− × β3+/+FcRn−/+. (B) Anti-FcRn monoclonal antibody injection during pregnancy. Low platelet counts are observed only in pups delivered from nontreated immunized female mice. N = platelet counts. (Professional illustration by Paulette Dennis.)