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About the Cover

December 01, 2007; 110 (12)

Cover image expansion

Tissue factor crystal structure with the sulfur atoms of the proposed labile Cys186-Cys209 disulfide bond in yellow. Does tissue factor encryption/decryption involve modification of this bond by protein disulfide isomerase? See article in this issue by Pendurthi et al (page 3900) and the accompanying Inside Blood commentary by Morrissey (page 3822).