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Immunobiology and Immunotherapy

  • Platelet-derived TLT-1 is a prognostic indicator in ALI/ARDS and prevents tissue damage in the lungs in a mouse model
    Jessica Morales-Ortíz, Victoria Deal, Fiorella Reyes, Gerónimo Maldonado-Martínez, Nahomy Ledesma, Franklin Staback, Cheyanne Croft, Amanda Pacheco, Humberto Ortiz-Zuazaga, C. Christian Yost, Jesse W. Rowley, Bismark Madera, Alex St. John, Junmei Chen, Jose Lopez, Matthew T. Rondina, Robert Hunter, Angelia Gibson and A. Valance Washington
  • Bifunctional PD-1 × αCD3 × αCD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia
    Monika Herrmann, Christina Krupka, Katrin Deiser, Bettina Brauchle, Anetta Marcinek, Ana Ogrinc Wagner, Felicitas Rataj, Ralph Mocikat, Klaus H. Metzeler, Karsten Spiekermann, Sebastian Kobold, Nadja C. Fenn, Karl-Peter Hopfner and Marion Subklewe
  • T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency
    Immacolata Brigida, Matteo Zoccolillo, Maria Pia Cicalese, Laurène Pfajfer, Federica Barzaghi, Serena Scala, Carmen Oleaga-Quintas, Jesus A. Álvarez-Álvarez, Lucia Sereni, Stefania Giannelli, Claudia Sartirana, Francesca Dionisio, Luca Pavesi, Marta Benavides-Nieto, Luca Basso-Ricci, Paola Capasso, Benedetta Mazzi, Jeremie Rosain, Nufar Marcus, Yu Nee Lee, Raz Somech, Massimo Degano, Giuseppe Raiola, Roberta Caorsi, Paolo Picco, Marcela Moncada Velez, Joelle Khourieh, Andrés Augusto Arias, Aziz Bousfiha, Thomas Issekutz, Andrew Issekutz, Bertrand Boisson, Kerry Dobbs, Anna Villa, Angelo Lombardo, Benedicte Neven, Despina Moshous, Jean-Laurent Casanova, José Luis Franco, Luigi D. Notarangelo, Cristina Scielzo, Stefano Volpi, Loïc Dupré, Jacinta Bustamante, Marco Gattorno and Alessandro Aiuti
  • Improving CLL Vγ9Vδ2-T–cell fitness for cellular therapy by ex vivo activation and ibrutinib
    Iris de Weerdt, Tom Hofland, Roeland Lameris, Sanne Endstra, Aldo Jongejan, Perry D. Moerland, Renee C. G. de Bruin, Ester B. M. Remmerswaal, Ineke J. M. ten Berge, Nora Liu, Mario van der Stelt, Laura M. Faber, Mark-David Levin, Eric Eldering, Sanne H. Tonino, Tanja D. de Gruijl, Hans J. van der Vliet and Arnon P. Kater
  • Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice
    Vedran Radojcic, Katelyn Paz, Jooho Chung, Jing Du, Eric T. Perkey, Ryan Flynn, Sanja Ivcevic, Michael Zaiken, Ann Friedman, Minhong Yan, Maria A. Pletneva, Stefanie Sarantopoulos, Christian W. Siebel, Bruce R. Blazar and Ivan Maillard
  • Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis
    Giovanna Lucchini, Rebecca Marsh, Kimberly Gilmour, Austen Worth, Zohreh Nademi, Anupama Rao, Claire Booth, Persis Amrolia, Juliana Silva, Robert Chiesa, Robert Wynn, Kai Lehmberg, Itziar Astigarraga, Tayfun Güngör, Jan Stary, Despina Moshous, Marianne Ifversen, Daniel Zinn, Michael Jordan, Ashish Kumar, Takahiro Yasumi, Paul Veys and Kanchan Rao
  • PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival
    Xiaoqing Lu, Tharu M. Fernando, Chen Lossos, Nevin Yusufova, Fan Liu, Lorena Fontán, Matthew Durant, Huimin Geng, Jacob Melnick, Yuan Luo, Francisco Vega, Vincent Moy, Giorgio Inghirami, Stephen Nimer, Ari M. Melnick and Izidore S. Lossos
  • Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma
    Amit Sud, Hauke Thomsen, Giulia Orlando, Asta Försti, Philip J. Law, Peter Broderick, Rosie Cooke, Fadi Hariri, Tomi Pastinen, Douglas F. Easton, Paul D. P. Pharoah, Alison M. Dunning, Julian Peto, Federico Canzian, Rosalind Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, Daniele Campa, the PRACTICAL Consortium, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Elke Pogge von Strandmann, Anthony J. Swerdlow, Andreas Engert, Nick Orr, Kari Hemminki and Richard S. Houlston
  • Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal?
    Yasodha Natkunam, Dita Gratzinger, Amy Chadburn, John R. Goodlad, John K. C. Chan, Jonathan Said, Elaine S. Jaffe and Daphne de Jong
  • Murine pre–B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor
    Haiying Qin, Kazusa Ishii, Sang Nguyen, Paul P. Su, Chad R. Burk, Bong-Hyun Kim, Brynn B. Duncan, Samikasha Tarun, Nirali N. Shah, M. Eric Kohler and Terry J. Fry

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